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R.C.L. Page, in Side Effects of Drugs Annual, 2010. Genetic. Previous studies have suggested that the pharmacokinetics of modified-release gliclazide (gliclazide MR) are highly variable in Chinese subjects but not in white populations. The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics of gliclazide have been ... Fetch Document
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Determined by side-effects and the duration of action as well as the patient’s age and renal function. The long-acting sulphonylureas chlorpropamide and glibenclamide are associated with a greater risk of hypoglycaemia; for this reason they should be avoided in the elderly and shorter-acting alternatives, such as gliclazide or ... Doc Retrieval
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Ethical approval was not sought for this retrospective observational study because gliclazide is widely used in the management of patients with type 2 diabetes controlled with insulin. The variation from standard practice was to re‐introduce gliclazide only when suboptimal control was achieved with insulin and maximum tolerated metformin. ... Retrieve Full Source
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Gliclazide MR by AA Pharma Inc.: Gliclazide modified release (MR) belongs to the class of medications called oral hypoglycemics. It is used for the control of blood glucose in people with type 2 diabetes. It is used when diet, exercise, and weight reduction have not been found to control blood glucose well enough without medication. ... Access Doc
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The effects of the drug are limited to areas containing β 1 adrenoreceptors, which is mainly the heart and part of the kidney. Bisoprolol minimizes the side effects that might occur from administration of a nonspecific beta blocker where blockage of the other adrenoreceptors (β 2, β 3, α 1, α 2) occurs. ... Read Article
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The Effects of Gliclazide, Metformin, and Acarbose on Body Composition in Patients with Newly Diagnosed Type 2 weight gain is a frequent side effect of antihyperglycemia therapy in patients with type 2 diabetes mellitus. 1–3 It has been shown that weight gain increases the risk of ... Fetch Here
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Gliclazide(Diamicron) generic is an oral hypoglycemic (anti-diabetic drug), prescribed for type 2 diabetesIt stimulates the pancreas, which helps in more insulin secretion. ... View Document
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It's used as first-line treatment because it's a generally tolerable drug (not many serious side effects) in most people, it's relatively affordable, and (importantly) it offers excellent glycaemic control (manages your blood sugar well). As an added bonus, in some people it reduces the risk of cardiovascular events like heart attacks. ... Access Full Source
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Summary: Drug interactions are reported among people who take Gliclazide and Simvastatin together. This study is created by eHealthMe based on reports of 2,009 people who take Gliclazide and Simvastatin from FDA, and is updated regularly. ... View Full Source
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By mouth using immediate-release medicines. For Adult. Initially 40–80 mg daily, adjusted according to response, increased if necessary up to 160 mg once daily, dose to be taken with breakfast, doses higher than 160 mg to be given in divided doses; maximum 320 mg per day. ... Access Content
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